Biocomposites-Coated Biodegradable Materials with Optimized Properties for Orthopedic Implant Biodegradability and Performance: A Comparative Study

Implant failure continues to be a critical concern in orthopedic interventions, frequently resulting in consequences such as fractures and necessitating revision procedures. Multiple causes, such as mechanical failure, inadequate osteointegration, and corrosion, lead to implant failure over time. This study seeks to resolve these challenges by surface-modifying biodegradable materials such as poly(lactic acid) (PLA) and AZ31 Mg alloy (Mg), integrating novel Biocomposites of titanium-hydroxyapatite (Ti-HA) to improve their efficacy. The altered materials aim to enhance mechanical strength, osteointegration, and regulated deterioration, thus minimizing the likelihood of implant failure. The characterization techniques validated the Biocomposites' adhesion on the implant's surface, mechanical analysis and corrosion resistance were also validated with the help of UTS and electrochemical studies, and <i>in vitro</i> analyses exhibited substantial improvements in material durability and biological compatibility. The result shows that the Biocomposite assistance improved the overall performance of the implant material. This work presents a pioneering strategy to mitigate implant failure by emphasizing these enhancements, facilitating more dependable and efficient solutions in orthopedic implantation, ultimately enhancing patient outcomes and decreasing the necessity for revision procedures. The earlier segment of the research study was confirmed with another Biocomposites (Ti-Zr), representing a continuation of that research work.

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Publication Details

Journal
ACS Applied Bio Materials
Published
2025-05-22
DOI
https://doi.org/10.1021/acsabm.5c00603
Citations
2
Primary Topic
Magnesium Alloys: Properties and Applications
Type
article
Field-Weighted Citation Impact
1.19

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article

Biocomposites-Coated Biodegradable Materials with Optimized Properties for Orthopedic Implant Biodegradability and Performance: A Comparative Study

Vamsi Krishna Dommeti, Hari Raj K, Gnanavel Sadasivam
2 citations
ACS Applied Bio Materials
Magnesium Alloys: Properties and Applications
1.19
article

Biocomposites-Coated Biodegradable Materials with Optimized Properties for Orthopedic Implant Biodegradability and Performance: A Comparative Study

Vamsi Krishna Dommeti, Hari Raj K, Gnanavel Sadasivam
article en
2 citations

Abstract

Implant failure continues to be a critical concern in orthopedic interventions, frequently resulting in consequences such as fractures and necessitating revision procedures. Multiple causes, such as mechanical failure, inadequate osteointegration, and corrosion, lead to implant failure over time. This study seeks to resolve these challenges by surface-modifying biodegradable materials such as poly(lactic acid) (PLA) and AZ31 Mg alloy (Mg), integrating novel Biocomposites of titanium-hydroxyapatite (Ti-HA) to improve their efficacy. The altered materials aim to enhance mechanical strength, osteointegration, and regulated deterioration, thus minimizing the likelihood of implant failure. The characterization techniques validated the Biocomposites' adhesion on the implant's surface, mechanical analysis and corrosion resistance were also validated with the help of UTS and electrochemical studies, and <i>in vitro</i> analyses exhibited substantial improvements in material durability and biological compatibility. The result shows that the Biocomposite assistance improved the overall performance of the implant material. This work presents a pioneering strategy to mitigate implant failure by emphasizing these enhancements, facilitating more dependable and efficient solutions in orthopedic implantation, ultimately enhancing patient outcomes and decreasing the necessity for revision procedures. The earlier segment of the research study was confirmed with another Biocomposites (Ti-Zr), representing a continuation of that research work.

ACS Applied Bio MaterialsVol. 8(6)
SRM Institute of Science and Technology (IN)
SRM Institute of Science and Technology, Science and Engineering Research Board
Openalex Percentile: Top 22%
Magnesium Alloys: Properties and Applications
1.19
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Biocomposites-Coated Biodegradable Materials with Optimized Properties for Orthopedic Implant Biodegradability and Performance: A Comparative Study — Vamsi Krishna Dommeti, Hari Raj K, et al. · ACS Applied Bio Materials (2025) | TGRS Research Map | TGRS