RefAHL: a curated quorum sensing reference linking diverse LuxI-type signal synthases with their acyl-homoserine lactone products
Some bacteria use acyl-homoserine lactone (AHL) signals in quorum sensing, a type of cell-cell communication. Here, we present "RefAHL," an updated, curated collection of LuxI-type AHL synthases with their AHL products and associated metadata. RefAHL is publicly available as a community resource to help catalog LuxI-type diversity encoded in (meta) genomic data.
Authors
- Ethan G. Murdock (ORCID: https://orcid.org/0000-0002-2624-5394)
- Aaron W. Puri (ORCID: https://orcid.org/0000-0002-6378-678X)
- Amy L. Schaefer (ORCID: https://orcid.org/0000-0003-0581-054X)
- Caroline S. Harwood (ORCID: https://orcid.org/0000-0003-4450-5177)
- Dale A. Pelletier (ORCID: https://orcid.org/0000-0002-4321-7918)
- E. Peter Greenberg (ORCID: https://orcid.org/0000-0001-9474-8041)
Institutions
- Oak Ridge National Laboratory (US)
- University of Washington (US)
- University of Utah (US)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1128/mra.00407-25
- Citations
- 1
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- U.S. Department of Energy
- National Science Foundation of Sri Lanka
- National Institute of General Medical Sciences