Imaging the lifecycle of <i>Microsporidia</i> sp. MB in <i>Anopheles coluzzii</i> from western Burkina Faso reveals octosporogony
Malaria in West Africa, caused by <i>Plasmodium falciparum</i> infection and spread by anopheline mosquitoes, is responsible for hundreds of thousands of deaths annually and resulted in over 120 million cases in 2022 . The transmission-blocking effect of <i>Microsporidia</i> sp. MB (MB) suggests its potential as an agent for combating the spread of malaria. Understanding the routes of transmission and their effect on MB in mosquito populations is crucial for its development as a control tool. The identification of MB spores reveals the potential for another avenue of transmission beyond the vertical transmission from female to offspring. Spores could also have the potential for alternative MB dissemination methods, alongside or instead of adult mosquito releases.
Authors
- Roland Pevsner (ORCID: https://orcid.org/0009-0002-3988-9583)
- Thomas H. Ant (ORCID: https://orcid.org/0000-0001-9911-4224)
- Abdoulaye Diabaté (ORCID: https://orcid.org/0000-0002-9666-9395)
- Issiaka Saré (ORCID: https://orcid.org/0000-0003-4216-134X)
- Deepak-Kumar Purusothaman (ORCID: https://orcid.org/0000-0003-4827-6519)
- Etienne Bilgo (ORCID: https://orcid.org/0000-0003-2350-9339)
- Ewan Parry (ORCID: https://orcid.org/0000-0002-4417-0365)
- Stephanie M. Rainey (ORCID: https://orcid.org/0000-0001-9504-5495)
- Steven P. Sinkins (ORCID: https://orcid.org/0000-0002-2678-1832)
- Beth C. Poulton (ORCID: https://orcid.org/0000-0002-9831-5697)
- A Adam
Institutions
- MRC University of Glasgow Centre for Virus Research (GB)
- Institut de Recherche en Sciences de la Santé (BF)
Publication Details
- Journal
- mSphere
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1128/msphere.00851-24
- Citations
- 3
- Primary Topic
- Insect symbiosis and bacterial influences
- Type
- article
- Field-Weighted Citation Impact
- 5.02
Funders
- Open Philanthropy Project