Urinary enterolignan concentrations and cardiometabolic risk biomarkers in pregnant US women
The results of our study showed that urinary excretion of enterolignans were inversely associated with cardiometabolic risk markers in pregnant women. These findings support further investigation on the role of lignans in modifying lipid and glucose metabolism. Given the high prevalence of maternal insulin resistance and hyperlipidemia and its serious health consequences for both women and their offspring, the use of lignans, if demonstrated to be efficacious, could provide a cost-effective option for curbing this epidemic by prevention and early treatment.
Authors
- Yuqing Zhang (ORCID: https://orcid.org/0000-0001-7954-1149)
- Tiffany A. Moore Simas (ORCID: https://orcid.org/0000-0002-8356-6418)
- Ling Shi (ORCID: https://orcid.org/0000-0002-5831-813X)
- Laura L. Hayman (ORCID: https://orcid.org/0000-0003-2146-4747)
- Qi Sun (ORCID: https://orcid.org/0000-0002-8480-1563)
- Alice H. Lichtenstein
Institutions
- Harvard University (US)
- University of Massachusetts Chan Medical School (US)
- University of Massachusetts Boston (US)
- Jean Mayer Human Nutrition Research Center on Aging (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Nutrition Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s12937-025-01143-3
- Citations
- 1
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 3.49