Placental Vascular Defects and Embryonic Lethality Triggered by TFPIα Deficiency in Factor V Leiden Mice
These findings suggest that TFPIα and its inhibition of prothrombinase play an important role in placental angiogenesis and embryonic survival.
Authors
- Alan E. Mast (ORCID: https://orcid.org/0000-0003-3740-0318)
- Amy E. Siebert (ORCID: https://orcid.org/0000-0002-9634-9164)
- Nicholas D. Martinez (ORCID: https://orcid.org/0000-0002-9315-9082)
- Susan A. Maroney (ORCID: https://orcid.org/0000-0002-8021-0694)
- Michael J. Soares (ORCID: https://orcid.org/0000-0001-7158-1592)
Institutions
- Medical College of Wisconsin (US)
- Versiti Blood Center of Wisconsin (US)
- University of Kansas Medical Center (US)
- Institut de Médecine de la Reproduction (FR)
- Mercy Research (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1161/atvbaha.125.322650
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00