Roles of Brd4 in Vascular Smooth Muscle Cells: Implications for Aging and Vascular Dysfunction
Brd4 depletion in SMCs induces senescence, prevents neointima formation, and exacerbates vascular aging, highlighting its crucial roles in vascular functions and diseases.
Authors
- Xi‐Long Zheng (ORCID: https://orcid.org/0000-0002-0889-1827)
- Darrell D. Belke (ORCID: https://orcid.org/0009-0002-4418-7201)
- Hao Yin (ORCID: https://orcid.org/0000-0002-0018-3228)
- Joseph A. Hill (ORCID: https://orcid.org/0000-0002-5379-1614)
- Binjie Yan (ORCID: https://orcid.org/0000-0002-1786-2374)
- Shenghua Zhou (ORCID: https://orcid.org/0000-0001-5388-7766)
- Yong-Xiang Chen (ORCID: https://orcid.org/0000-0002-8156-147X)
- Yu Gui (ORCID: https://orcid.org/0000-0001-6438-1170)
- Jiaxing Sun (ORCID: https://orcid.org/0000-0002-2808-0079)
Institutions
- Western University (CA)
- Central South University (CN)
- Army Medical University (CN)
- University of Calgary (CA)
- Southwest Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Arteriosclerosis Thrombosis and Vascular Biology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1161/atvbaha.124.322158
- Citations
- 1
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.81