N-phenylmaleimide induces bioenergetic switch and suppresses tumor growth in glioblastoma tumorspheres by inhibiting SLC25A11
Targeting GBM bioenergetics using KN612 may represent a novel and effective approach for GBM treatment.
Authors
- Jong Hee Chang (ORCID: https://orcid.org/0000-0003-1509-9800)
- Jae‐Seon Lee (ORCID: https://orcid.org/0000-0001-6002-5267)
- Soo‐Youl Kim (ORCID: https://orcid.org/0000-0002-4021-2206)
- Eui Hyun Kim (ORCID: https://orcid.org/0000-0002-2523-7122)
- Jihwan Yoo (ORCID: https://orcid.org/0000-0001-8746-1245)
- Junseong Park (ORCID: https://orcid.org/0000-0003-0436-8614)
- Wan‐Yee Teo (ORCID: https://orcid.org/0000-0002-1046-1674)
- Ju Hyung Moon (ORCID: https://orcid.org/0000-0002-8925-5821)
- Seok‐Gu Kang (ORCID: https://orcid.org/0000-0001-5676-2037)
- Hye Joung Cho
- Ran Joo Choi (ORCID: https://orcid.org/0000-0001-5024-8221)
- Ryong Nam Kim
Institutions
- Agency for Science, Technology and Research (SG)
- Yonsei University (KR)
- Severance Hospital (KR)
- National Cancer Center (US)
- National Cancer Center (KR)
- Duke-NUS Medical School (SG)
- Gangnam Severance Hospital (KR)
- Institute of Molecular and Cell Biology (SG)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s12935-025-03813-y
- Citations
- 4
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.50
Funders
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Yonsei University College of Medicine