Poly- and perfluoroalkyl substances (PFAS) in the first 1000 days reduce linear growth, lean body mass and bone mineral density at age 3 years
Higher plasma PFAS levels in 'the first 1000 days' of life were negatively associated with height, LBM and BMD SDS at age 3 years, while exclusive breastfeeding during the first 3 months of life was positively associated with these outcomes. This suggest that early life plasma PFAS levels could jeopardize breastfeeding's known health benefits, which warrants further research.
Authors
- Inge A.L.P. van Beijsterveldt (ORCID: https://orcid.org/0000-0002-0204-7430)
- Demi J. Dorrepaal (ORCID: https://orcid.org/0009-0001-7487-1234)
- Bertrand D. van Zelst (ORCID: https://orcid.org/0000-0001-9148-399X)
- Sjoerd A.A. van den Berg (ORCID: https://orcid.org/0000-0001-5937-7505)
- Anita C. S. Hokken‐Koelega
Institutions
- Erasmus MC (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
Publication Details
- Journal
- Clinical Nutrition
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.clnu.2025.05.017
- Citations
- 6
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 5.16