Veillonella and Streptococcus are associated with aging of the gut microbiota and affect the efficacy of immune checkpoint inhibitors
These gut microbiota changes with aging, and its characteristics are important parameters that also affect the efficacy of ICIs.
Authors
- Takuya Tsunoda (ORCID: https://orcid.org/0000-0002-6416-8211)
- Takehiko Sambe (ORCID: https://orcid.org/0000-0001-6730-7873)
- Toshiaki Tsurui (ORCID: https://orcid.org/0000-0002-6167-8953)
- Eiji Funayama
- Yutaro Kubota (ORCID: https://orcid.org/0000-0002-2917-8764)
- Kiyoshi Yoshimura (ORCID: https://orcid.org/0000-0003-4816-1826)
- Atsuo Kuramasu
- Midori Shida
- Shinichi Kobayashi (ORCID: https://orcid.org/0000-0002-5600-5826)
- Naoki Uchida (ORCID: https://orcid.org/0000-0002-4220-9625)
- Y Maruyama
- Yuta Baba (ORCID: https://orcid.org/0000-0002-5743-0306)
- Hirotsugu Ariizumi (ORCID: https://orcid.org/0000-0003-1663-8730)
- Yasunobu Amari
- Ryotaro Ohkuma (ORCID: https://orcid.org/0000-0003-4121-2491)
- Atsushi Horiike (ORCID: https://orcid.org/0000-0002-1632-3125)
- Masakazu Murayama
- Yoichiro Narikawa
- Hitoshi Toyoda
- Junya Isobe
- Tomoyuki Ishiguro
- Masahiro Shimokawa (ORCID: https://orcid.org/0000-0002-8645-4112)
- Satoshi Wada (ORCID: https://orcid.org/0000-0001-6528-5914)
- Nana Iriguchi
- Yuji Kiuchi (ORCID: https://orcid.org/0000-0001-7198-3735)
- Masahiro Hosonuma (ORCID: https://orcid.org/0000-0002-5861-7543)
- Yuya Hirasawa
- Aya Sasaki
- Emiko Mura
- Kohei Tajima
- Risako Suzuki
Institutions
- SHOWA Medical University (JP)
- Tokai University (JP)
- Therapeutics Clinical Research (US)
- SHOWA Medical University Fujigaoka Hospital (JP)
- SHOWA Medical University Hospital (JP)
- Showa Pharmaceutical University (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1528521
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 3.22