Physical activity affects DNA methylation-derived inflammation markers in a community-based Parkinson's disease study
PA may benefit PD patients by reducing chronic inflammation. We also found that strenuous PA may increase the proportions of NK and CD8T cells, though further effort is needed to confirm potential shifts in immune cell subtypes.
Authors
- Cynthia Kusters (ORCID: https://orcid.org/0000-0001-8099-9026)
- Jeff M. Bronstein (ORCID: https://orcid.org/0000-0002-2961-8918)
- Kimberly C. Paul (ORCID: https://orcid.org/0000-0002-4476-2352)
- Jin Zhou (ORCID: https://orcid.org/0000-0003-0372-2554)
- Beate R. Ritz (ORCID: https://orcid.org/0000-0001-6976-7339)
- Yang Hu (ORCID: https://orcid.org/0009-0004-9289-5514)
- Keren Zhang
Institutions
- University of California, Los Angeles (US)
- UCLA Health (US)
- Neurobehavioral Systems (US)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.bbih.2025.101014
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81