Fibrinogen Depletion Coagulopathy and Hemorrhagic Transformation in Acute Ischemic Stroke Treated With Bridging Therapy
Following bridging therapy, FDC is a frequent event associated with increased risks of any HT, symptomatic HT, parenchymal hematomas, and 3-month mortality. FDC did not occur following IVT with tenecteplase in our cohort, suggesting that the fibrin specificity of thrombolytic agents may play a pivotal role in its development.
Authors
- Stanislas Smajda
- Mialitiana Solo Nomenjanahary
- Hong‐Anh Cung
- Pierre Seners (ORCID: https://orcid.org/0000-0002-2134-0691)
- Candice Sabben
- Simon Escalard (ORCID: https://orcid.org/0000-0003-1306-1008)
- Erwan Robichon
- Simon Clariot (ORCID: https://orcid.org/0000-0003-3162-2155)
- Julien Fournier
- David Weisenburger
- Andrea Raisi (ORCID: https://orcid.org/0000-0002-0096-4534)
- Perrine Boursin
- Philippa C. Lavallée
- Grace Adwane (ORCID: https://orcid.org/0000-0001-7789-6093)
- Nicolas Chausson (ORCID: https://orcid.org/0000-0002-3512-1385)
- Hocine Redjem (ORCID: https://orcid.org/0000-0002-6943-9922)
- Julien Savatovsky (ORCID: https://orcid.org/0000-0002-6732-1779)
- Véronique Ollivier (ORCID: https://orcid.org/0000-0003-1318-1712)
- Mélanie Souvanheuane
- Nahida Brikci-Nigassa
- Chloé Le Cossec
- Jean‐Philippe Désilles (ORCID: https://orcid.org/0000-0001-8395-6312)
- Benjamin Maïer (ORCID: https://orcid.org/0000-0003-3993-1024)
- Dorothée Faille (ORCID: https://orcid.org/0000-0003-4414-739X)
- François Delvoye (ORCID: https://orcid.org/0000-0002-0697-2156)
- Mikaël Mazighi (ORCID: https://orcid.org/0000-0003-0911-8999)
- Gaspard Gerschenfeld (ORCID: https://orcid.org/0000-0002-2456-704X)
- Tristan Benoit
- Olivier Ille
- Aurélien Freiherr von Seckendorff (ORCID: https://orcid.org/0000-0003-4051-5351)
- Cristina Hobeanu (ORCID: https://orcid.org/0000-0002-9131-3496)
- Alain Améri
- Amélie Yavchitz (ORCID: https://orcid.org/0000-0002-9911-8556)
- Benoît Ho‐Tin‐Noé
- Michaël Obadia (ORCID: https://orcid.org/0000-0002-4221-6163)
- Louis Colrat
- Raphaël Blanc (ORCID: https://orcid.org/0000-0002-3975-3865)
- Nicolas Engrand (ORCID: https://orcid.org/0000-0002-6051-5474)
- Augustin Gaudemer (ORCID: https://orcid.org/0000-0002-0823-3496)
- Michel Piotin
- Igor Raynouard
- Jean‐Michel Devys
- Pierre Trouiller
- Fatima Zemali
- Naëiri Pauillac
- William Boissseau
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Inserm (FR)
- Délégation Paris 7 (FR)
- Institut Universitaire de France (FR)
- Université Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Sud Francilien (FR)
- Hôpital Lariboisière (FR)
- Fondation de Rothschild (FR)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- Centre Hospitalier Universitaire de Liège (BE)
- Hôpital Paris Saint-Joseph (FR)
- FHU Neurovasc (FR)
- Hôpital Bichat-Claude-Bernard (FR)
- Centre hospitalier Robert-Ballanger (FR)
- French Clinical Research Infrastructure Network (FR)
Publication Details
- Journal
- Stroke
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1161/strokeaha.125.051230
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71