The Effects of Glucagon-Like Peptide-1 Agonist Therapy on Risk of Infection, Fracture, and Early Revision in Primary Total Joint Arthroplasty
In this retrospective study of both TKA and THA among diabetic patients, we found that patients using GLP-1 agonists had a lower rate of periprosthetic infection following TKA. The benefits of GLP-1 therapy might limit infection risk, however additional research is needed to understand the effect these medications make on patient nutrition and bone metabolism.
Authors
- Michael F. Levidy (ORCID: https://orcid.org/0000-0003-1591-8466)
- Gregory J. Kirchner (ORCID: https://orcid.org/0000-0003-0959-0222)
- Nishant Gohel (ORCID: https://orcid.org/0000-0002-9491-1969)
- Mark W. Mason (ORCID: https://orcid.org/0000-0002-7793-0674)
- Nicholas Rowe (ORCID: https://orcid.org/0000-0002-6968-9251)
- Sohrab Vatsia (ORCID: https://orcid.org/0000-0002-6871-0629)
- Spencer Demedal
Institutions
- Medical Protective (US)
Publication Details
- Journal
- Journal of the American Academy of Orthopaedic Surgeons
- Published
- 2025-05-09
- DOI
- https://doi.org/10.5435/jaaos-d-24-01284
- Citations
- 11
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 22.07