Extracellular Inosine Induces Anergy in B Cells to Alleviate Autoimmune Hepatitis
Our findings revealed that inosine was a crucial metabolite that induced immune tolerance of B cells, thus proposing a potential intervention strategy for AIH.
Authors
- Nana Cui
- Yujie Zhou (ORCID: https://orcid.org/0000-0002-6740-9818)
- Xiong Ma (ORCID: https://orcid.org/0000-0001-9616-4672)
- Heng Zhang (ORCID: https://orcid.org/0009-0007-7004-9255)
- Yikang Li (ORCID: https://orcid.org/0000-0003-4772-3233)
- Huayang Zhang (ORCID: https://orcid.org/0000-0002-5540-3435)
- Min Lian (ORCID: https://orcid.org/0000-0003-2122-1614)
- Zhengrui You
- Qixia Wang (ORCID: https://orcid.org/0000-0001-6759-530X)
- Qiwei Qian
- Bing-Hong Wang
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Sciences (CN)
- Renji Hospital (CN)
- Shanghai Institute of Materia Medica (CN)
- State Key Laboratory of Oncogene and Related Genes (CN)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101539
- Citations
- 2
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 2.64