One-pot assembly of functionalized (<em>m</em>-terphenyl-4'-yl)isoquinolines from 1-methylisoquinoline and electrophilic acylacetylenes
The relative reactivity of deprotonated CH<sub>3</sub> group and nitrogen atom of 1-methylisoquinoline towards electrophilic triple bond crucially depends on the acetylene structure and the reaction conditions. 1-Acyl-2-arylacetylenes react with 1-methylisoquinoline in a 2 : 1 molar ratio (34 mol in trace to 11
Authors
- А. В. Афонин (ORCID: https://orcid.org/0000-0001-7916-2421)
- Lina P. Nikitina (ORCID: https://orcid.org/0000-0002-7171-1868)
- Igor А. Ushakov (ORCID: https://orcid.org/0000-0003-0176-1699)
- Kseniya V. Belyaeva (ORCID: https://orcid.org/0000-0002-7880-7555)
- Б. А. Трофимов (ORCID: https://orcid.org/0000-0002-0430-3215)
- Alexander V. Vashchenko (ORCID: https://orcid.org/0000-0002-3188-9979)
- Veronika S. Saliy
Institutions
- A.E. Favorsky Irkutsk Institute of Chemistry (RU)
Publication Details
- Journal
- Mendeleev Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.71267/mencom.7695
- Citations
- 1
- Primary Topic
- Synthesis and Characterization of Pyrroles
- Type
- article
- Field-Weighted Citation Impact
- 0.94