Hydroxycarbonylation of vinyl acetate with formic acid: pathway to lactic acid and lactates

The Pd-catalyzed hydroxycarbonylation of vinyl acetate in the presence of formic acid into 2-acetoxypropionic acid is reported. The reaction proceeds chemo- and regioselectively under very mild conditions of 80 °C and 3-6 bar CO.

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Publication Details

Journal
Mendeleev Communications
Published
2025-01-01
DOI
https://doi.org/10.71267/mencom.7657
Primary Topic
biodegradable polymer synthesis and properties
Type
article
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0.00
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article

Hydroxycarbonylation of vinyl acetate with formic acid: pathway to lactic acid and lactates

О. Л. Елисеев, М. В. Цапкина, T. N. Bondarenko
Mendeleev Communications
biodegradable polymer synthesis and properties
article

Hydroxycarbonylation of vinyl acetate with formic acid: pathway to lactic acid and lactates

О. Л. Елисеев, М. В. Цапкина, T. N. Bondarenko
article en

Abstract

The Pd-catalyzed hydroxycarbonylation of vinyl acetate in the presence of formic acid into 2-acetoxypropionic acid is reported. The reaction proceeds chemo- and regioselectively under very mild conditions of 80 °C and 3-6 bar CO.

Mendeleev CommunicationsVol. 35(4)
N.D. Zelinsky Institute of Organic Chemistry (RU)
Openalex Percentile: Top 93%
biodegradable polymer synthesis and properties
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Hydroxycarbonylation of vinyl acetate with formic acid: pathway to lactic acid and lactates — О. Л. Елисеев, М. В. Цапкина, et al. · Mendeleev Communications (2025) | TGRS Research Map | TGRS