Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross‐Over Study in Healthy Volunteers
Whole gut transit time changes significantly affect fecal microbiome composition and function, as well as bile acid composition and synthesis in healthy subjects. This consideration is likely to have long-term implications.
Authors
- Evette B. Hillman (ORCID: https://orcid.org/0000-0002-4896-4621)
- Danielle Carson (ORCID: https://orcid.org/0000-0003-1200-2022)
- Ramesh Pulendran Arasaradnam (ORCID: https://orcid.org/0000-0002-2231-3062)
- Gregory C. A. Amos (ORCID: https://orcid.org/0000-0001-9748-1813)
- Malik A. Khan
- Sjoerd Rijpkema (ORCID: https://orcid.org/0000-0003-0389-8904)
- Elizabeth M. H. Wellington (ORCID: https://orcid.org/0000-0002-4329-0699)
- Haider Ali Khan (ORCID: https://orcid.org/0000-0003-0586-3633)
- Julian R.F. Walters (ORCID: https://orcid.org/0000-0001-9720-5835)
- Maximilian Baumgartner (ORCID: https://orcid.org/0000-0002-9048-0233)
- Stephen J. Lewis (ORCID: https://orcid.org/0000-0002-4862-6139)
- Imad Wazir
Institutions
- Austrian Academy of Sciences (AT)
- Imperial College Healthcare NHS Trust (GB)
- University of Warwick (GB)
- CeMM Research Center for Molecular Medicine (AT)
- Coventry (United Kingdom) (GB)
- Imperial College London (GB)
- Medical University of Vienna (AT)
- University of Plymouth (GB)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1111/nmo.70075
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Health and Social Care
- University of Warwick