circ_EPB41 Modulates the miR-15a-5p/Bcl-2 Pathway to Alleviate Oxidative Stress Damage in Lens Epithelial Cells
This study is the first to demonstrate that up-regulation of circ_EPB41 protects lens epithelial cells from oxidative stress-induced apoptosis through the miR-15a-5p/Bcl-2 pathway. These findings suggest that circ_EPB41 may hold potential as a novel therapeutic target for age-related cataract treatment.
Authors
- Shaodan Hu (ORCID: https://orcid.org/0000-0003-1177-0679)
- Huanjie Fang (ORCID: https://orcid.org/0000-0003-0429-6059)
- Jie Fu (ORCID: https://orcid.org/0000-0002-3183-453X)
- Lifen Huang
- Shiyao Huang
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhuhai People's Hospital (CN)
- CM Hospital (KR)
Publication Details
- Journal
- Current Eye Research
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1080/02713683.2025.2506116
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81