Determination of Azilsartanmedoxomil by Visible Spectrophotometry

Abstract: A simple and reproducible spectrophotometric method has been developed for the determination of Azilsartanmedoxomilin bulk and pharmaceutical dosage forms. The method is based on the extraction of the drug into organic layer of the dye TPooo in presence of 0.1 N hydrochloric acid and the absorbances were measured at 485 nm. The method was optimized using eight parameters. The linearity range of Azilsartanmedoxomil with TPooo was found to be 0.5 – 3.0 ml; 400 µg/ml. The developed method was found to be precise and accurate from the statistical validation of the analytical data. The proposed method has been successfully applied for analysis of dosage formulations.