Fe-Doped Carbon Dots Alleviated Rheumatoid Arthritis by Inhibiting Neutrophil NETosis and Autophagy
This study demonstrates that MM-CDs represent a novel and effective therapeutic strategy for RA. Importantly, the treatment exhibited no liver or kidney toxicity in the RA mouse model, highlighting its potential for safe clinical translation.
Authors
- Xun Gong (ORCID: https://orcid.org/0000-0002-3377-0373)
- Congmin Xia
- Kai Yuan (ORCID: https://orcid.org/0000-0001-7239-449X)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-6140-3757)
- Hesong Wang (ORCID: https://orcid.org/0000-0003-1920-4700)
- Yali Zhou
- Aimin Yan
- Huaijuan Huang
- Guangrui Huang (ORCID: https://orcid.org/0000-0001-9621-8159)
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- ACS Biomaterials Science & Engineering
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1021/acsbiomaterials.4c01880
- Citations
- 1
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China
- Beijing University of Chinese Medicine
- China Academy of Chinese Medical Sciences