Using a naturally occurring sterility gene to control invasive house mice

House mice (Mus musculus) are a major ecosystem pest with devastating impact on island ecosystems as non-native invasive species.Current control methods -primarily aerial broadcasting of anticoagulant poisons-raise serious concerns about animal welfare, cause off-target impacts on other species, and are challenging to use in human-inhabited areas.Our research investigates an alternative control strategy using a naturally occurring genetic variant in mice, known as the t-haplotype, as a humane and targeted alternative for mouse population management.