Examining the Relation between Virus Mutation and Vaccination. A Data Analysis.

Public-domain available data documents the dynamics of variance characteristic of the COVID-19 pandemic. The enormous, but fractured, vaccination effort, and the still surprising dynamics of variants suggest possible inferences. The premise of the data analysis subject of this report is that vaccination, as an anticipatory action, is supposed to be preventive. The timeline of vaccine development for the large number of coronavirus forms suggests that the window of opportunity for prevention was missed. As a consequence, medicine was asked to react by finding means and methods for controlling the parameters of a pandemic. Various interventions were pursued under the pressure of the situation. As the record shows, such interventions can result in intentional or unintentional selective pressure on the virus associated with pandemic. The hypothesis that this pressure may favor the emergence of variants informs the research presented in this study. We examined mutations that result in partial immune evasion, not as an accident, but in connection to the vaccination effort. The data analysis performed suggests that the occurrence and frequency of vaccine-resistant mutations correlate with vaccination rates in certain regions.

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Publication Details

Journal
Journal of Vaccinology JV
Published
2025-04-14
DOI
https://doi.org/10.29245/2694-068x/2025/1.1101
Primary Topic
Vaccine Coverage and Hesitancy
Type
article
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article

Examining the Relation between Virus Mutation and Vaccination. A Data Analysis.

Ayush Sharma, G. C. Shekar, Mihai Nadin
Journal of Vaccinology JV
Vaccine Coverage and Hesitancy
article

Examining the Relation between Virus Mutation and Vaccination. A Data Analysis.

Ayush Sharma, G. C. Shekar, Mihai Nadin
article en

Abstract

Public-domain available data documents the dynamics of variance characteristic of the COVID-19 pandemic. The enormous, but fractured, vaccination effort, and the still surprising dynamics of variants suggest possible inferences. The premise of the data analysis subject of this report is that vaccination, as an anticipatory action, is supposed to be preventive. The timeline of vaccine development for the large number of coronavirus forms suggests that the window of opportunity for prevention was missed. As a consequence, medicine was asked to react by finding means and methods for controlling the parameters of a pandemic. Various interventions were pursued under the pressure of the situation. As the record shows, such interventions can result in intentional or unintentional selective pressure on the virus associated with pandemic. The hypothesis that this pressure may favor the emergence of variants informs the research presented in this study. We examined mutations that result in partial immune evasion, not as an accident, but in connection to the vaccination effort. The data analysis performed suggests that the occurrence and frequency of vaccine-resistant mutations correlate with vaccination rates in certain regions.

Journal of Vaccinology JVVol. 4(1)
Openalex Percentile: Top 86%
Vaccine Coverage and Hesitancy
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Examining the Relation between Virus Mutation and Vaccination. A Data Analysis. — Ayush Sharma, G. C. Shekar, et al. · Journal of Vaccinology JV (2025) | TGRS Research Map | TGRS