Cinnamend: Evaluating the Use of Kaningag (Cinnamomum Mindanaense Elm.) Leaf Extract as an Active Ingredient in Antibacterial Ointment against Escherichia Coli

Advancements in wound care offer practical solutions, but the rise of antibiotic-resistant bacteria like Escherichia coli poses a growing threat, demanding urgent alternative approaches to infection management. This study aimed to evaluate the antibacterial effect of kaningag (Cinnamomum mindanaense Elm.) leaf extract as an ointment against E. coli and to compare its effectiveness across different concentrations (2.5%, 5%, 7.5%, and 10%) with a control treatment. A posttest-only experimental design was employed, where treatments were applied to Petri dishes inoculated with E. coli. Results showed that the 10% concentration (T4) exhibited significantly greater antibacterial activity (31 mm) compared to the 2.5% concentration (T1) and negative control (petroleum jelly). T4’s effectiveness was comparable to the positive control (terramycin) at 20 mm. Statistical analysis revealed no significant differences among the other concentrations (T1, T2, T3), suggesting similar antibacterial effects. These findings indicate that kaningag leaf extract, particularly at higher concentrations, shows promise as a natural antibacterial agent. Given the increasing resistance of E. coli to conventional antibiotics, kaningag represents a potential alternative treatment, warranting further investigation for broader therapeutic applications.