Level of reactive oxygen species production in peripheral blood monocytes in patients with Graves’ disease after radioiodine therapy

Reduced metabolic activity of monocytes and low levels of ROS synthesis correlate with inhibition of the autoimmune process and decreased activation of the macrophage-monocyte system. The study confirms the importance of the role of monocytes in the ROS production system and their influence on the autoimmune process in Graves' disease. These results may have clinical significance and contribute to the development of new immunotropic strategies for the treatment of this disease.