On the moral (in)equivalence of human embryos and stem cell-derived embryo models

Gyngell <i>et al</i> argue that no intrinsic differences exist between stem cell-derived embryo models (SCEMs) and embryos derived from fertilisation that would justify attributing a higher moral status to the latter. Consequently, they claim there is no ethical rationale for treating SCEMs differently from embryos and contend that endorsing SCEMs as having moral advantages over embryos constitutes an obfuscation. In this commentary, we challenge the assertion that human SCEMs and embryos are morally equivalent by painting a more nuanced picture of the moral value of (different kinds of) SCEMs and embryos. First, we highlight the diversity among SCEMs, noting that different types of SCEMs need not be morally equivalent. This point is illustrated by taking a closer look at their potentiality, a property often considered relevant to moral status. Second, we observe that Gyngell <i>et al</i>, like much of the broader debate, primarily concentrate on the direct moral status of SCEMs in their analysis of the moral (in)equivalence with embryos. We argue that a comprehensive moral evaluation should encompass different types of moral value, evaluating not only direct moral status but also relational, symbolic and instrumental value. Ultimately, we suggest that the real obfuscation lies not in endorsing SCEMs as having moral advantages over embryos but rather in the overemphasis on direct moral status and the binary thinking about the moral (in)equivalence of embryos versus SCEMs that dominates these discussions.

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Publication Details

Journal
Journal of Medical Ethics
Published
2025-05-19
DOI
https://doi.org/10.1136/jme-2025-110866
Citations
3
Primary Topic
Biomedical Ethics and Regulation
Type
article
Field-Weighted Citation Impact
3.49

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article

On the moral (in)equivalence of human embryos and stem cell-derived embryo models

Lien De Proost, Nienke de Graeff
3 citations
Journal of Medical Ethics
Biomedical Ethics and Regulation
3.49
article

On the moral (in)equivalence of human embryos and stem cell-derived embryo models

Lien De Proost, Nienke de Graeff
article en
3 citations

Abstract

Gyngell <i>et al</i> argue that no intrinsic differences exist between stem cell-derived embryo models (SCEMs) and embryos derived from fertilisation that would justify attributing a higher moral status to the latter. Consequently, they claim there is no ethical rationale for treating SCEMs differently from embryos and contend that endorsing SCEMs as having moral advantages over embryos constitutes an obfuscation. In this commentary, we challenge the assertion that human SCEMs and embryos are morally equivalent by painting a more nuanced picture of the moral value of (different kinds of) SCEMs and embryos. First, we highlight the diversity among SCEMs, noting that different types of SCEMs need not be morally equivalent. This point is illustrated by taking a closer look at their potentiality, a property often considered relevant to moral status. Second, we observe that Gyngell <i>et al</i>, like much of the broader debate, primarily concentrate on the direct moral status of SCEMs in their analysis of the moral (in)equivalence with embryos. We argue that a comprehensive moral evaluation should encompass different types of moral value, evaluating not only direct moral status but also relational, symbolic and instrumental value. Ultimately, we suggest that the real obfuscation lies not in endorsing SCEMs as having moral advantages over embryos but rather in the overemphasis on direct moral status and the binary thinking about the moral (in)equivalence of embryos versus SCEMs that dominates these discussions.

Journal of Medical EthicsVol. 51(12)
Leiden University Medical Center (NL)
ZonMw
Openalex Percentile: Top 8%
Biomedical Ethics and Regulation
3.49
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On the moral (in)equivalence of human embryos and stem cell-derived embryo models — Lien De Proost, Nienke de Graeff · Journal of Medical Ethics (2025) | TGRS Research Map | TGRS