Direct Thrombin Inhibitors Suppress Type 1 Diabetes Development through PI3K/p-AKT Pathway
The evidence supported the activation of coagulation cascade in T1DM through the PI3K/AKT pathway. Using direct antithrombin therapy may open new avenues for T1DM prevention in high-risk diabetes individuals.
Authors
- Mohamed S. Abdel‐Bakky (ORCID: https://orcid.org/0000-0002-0426-5458)
- Ahmad Alhowail (ORCID: https://orcid.org/0000-0003-1427-032X)
- Hussien M. Ali
- Maha A. Aldubayan (ORCID: https://orcid.org/0000-0002-3277-1702)
- Ahmad Alharbi (ORCID: https://orcid.org/0000-0001-8135-2785)
Institutions
- Qassim University (SA)
- Al-Azhar University (EG)
- Northern Area Armed Forces Hospital (SA)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.2174/0118761429374852250305153445
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00