Targeting Phosphatase and Tensin Homolog Deleted on Chromosome10q23.3 (PTEN) as a Potential Theragnostic Biomarker in Tumors
This study suggests that PTEN may be involved in the recruitment and regulation of immune-infiltrating cells, tumor development, metastasis, prognosis, tumor immune escape, and immunotherapy, indicating its importance in tumor diagnosis and treatment.
Authors
- Jialiang Hui (ORCID: https://orcid.org/0000-0002-9879-9388)
- Ying Liu (ORCID: https://orcid.org/0000-0003-0802-3832)
- Li Tian (ORCID: https://orcid.org/0000-0003-0222-7076)
- Lifen Zhang (ORCID: https://orcid.org/0000-0002-1055-4790)
- Shuhua He (ORCID: https://orcid.org/0000-0002-0162-2536)
Institutions
- Nanfang Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Twelfth Guangzhou City People's Hospital (CN)
- Southern Medical University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Recent Patents on Anti-Cancer Drug Discovery
- Published
- 2025-05-19
- DOI
- https://doi.org/10.2174/0115748928370540250508101925
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00