Comparison of the Effects of Spinal Anaesthesia on Frontal QRS-T Angle in Term and Post-Term Pregnancies Planned for Elective Caesarean Section: A Prospective Study

<i>Background and Objectives</i>: Post-term pregnancies are associated with increased risks of perinatal complications. This study aimed to evaluate potential cardiac electrophysiological changes in pregnant women by comparing the QRS duration, interval of corrected QT (QTc), and frontal QRS-T angle [f(QRS-T)] between term and post-term pregnancies. <i>Materials and Methods</i>: In this observational prospective study, 120 pregnant women were enrolled-60 term (37-41 weeks) and 60 post-term (≥42 weeks). All participants underwent standard 12-lead electrocardiography (ECG) and caesarean section with spinal anaesthesia. The QTc interval, QRS duration, and frontal QRS-T angle were measured. Demographic parameters such as age, gestational week, height, and weight were recorded. The SPSS software was used to analyse the data with <i>p</i> < 0.05 as the threshold for significance. <i>Results</i>: Post-operative QTc interval (417.3 ± 20.5 vs. 410.2 ± 14.5, <i>p</i> = 0.032) and f(QRS-T) (28 [16-55] vs. 22 [14-34], <i>p</i> = 0.042) were significantly higher in the post-term group than in the term group. When the change in the f(QRS-T) angle was analysed, there was a significant widening of this angle in the post-term group (from 21 [11-37] to 28 [16-55], <i>p</i> = 0.002). The increased f(QRS-T) angle reflects greater heterogeneity in ventricular depolarisation and repolarisation, which may indicate sub-clinical myocardial stress or altered autonomic regulation in the post-term period. Although no overt arrhythmias were observed, subtle changes in P-wave morphology and QT dispersion were more prevalent in the post-term group. <i>Conclusions</i>: Prolonged QRS duration and an increased f(QRS-T) angle in post-term pregnancies can reflect the underlying changes in cardiac electrophysiology related to prolonged gestation. These ECG parameters may serve as non-invasive indicators of sub-clinical cardiac stress, which could be relevant for anaesthetic risk assessment and perinatal management.

Authors

Institutions

Publication Details

Journal
Medicina
Published
2025-05-19
DOI
https://doi.org/10.3390/medicina61050919
Citations
2
Primary Topic
Cardiovascular Issues in Pregnancy
Type
article
Field-Weighted Citation Impact
2.78
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparison of the Effects of Spinal Anaesthesia on Frontal QRS-T Angle in Term and Post-Term Pregnancies Planned for Elective Caesarean Section: A Prospective Study

Alev Esercan, Zülkif Tanrıverdi, Mahmut Alp Karahan, Tuğba Bingöl Tanrıverdi et al.
2 citations
Medicina
Cardiovascular Issues in Pregnancy
2.78
article

Comparison of the Effects of Spinal Anaesthesia on Frontal QRS-T Angle in Term and Post-Term Pregnancies Planned for Elective Caesarean Section: A Prospective Study

Alev Esercan, Zülkif Tanrıverdi, Mahmut Alp Karahan, Tuğba Bingöl Tanrıverdi, Ahmet Kaya, Melike Bostanci Erkmen
article en
2 citations

Abstract

<i>Background and Objectives</i>: Post-term pregnancies are associated with increased risks of perinatal complications. This study aimed to evaluate potential cardiac electrophysiological changes in pregnant women by comparing the QRS duration, interval of corrected QT (QTc), and frontal QRS-T angle [f(QRS-T)] between term and post-term pregnancies. <i>Materials and Methods</i>: In this observational prospective study, 120 pregnant women were enrolled-60 term (37-41 weeks) and 60 post-term (≥42 weeks). All participants underwent standard 12-lead electrocardiography (ECG) and caesarean section with spinal anaesthesia. The QTc interval, QRS duration, and frontal QRS-T angle were measured. Demographic parameters such as age, gestational week, height, and weight were recorded. The SPSS software was used to analyse the data with <i>p</i> < 0.05 as the threshold for significance. <i>Results</i>: Post-operative QTc interval (417.3 ± 20.5 vs. 410.2 ± 14.5, <i>p</i> = 0.032) and f(QRS-T) (28 [16-55] vs. 22 [14-34], <i>p</i> = 0.042) were significantly higher in the post-term group than in the term group. When the change in the f(QRS-T) angle was analysed, there was a significant widening of this angle in the post-term group (from 21 [11-37] to 28 [16-55], <i>p</i> = 0.002). The increased f(QRS-T) angle reflects greater heterogeneity in ventricular depolarisation and repolarisation, which may indicate sub-clinical myocardial stress or altered autonomic regulation in the post-term period. Although no overt arrhythmias were observed, subtle changes in P-wave morphology and QT dispersion were more prevalent in the post-term group. <i>Conclusions</i>: Prolonged QRS duration and an increased f(QRS-T) angle in post-term pregnancies can reflect the underlying changes in cardiac electrophysiology related to prolonged gestation. These ECG parameters may serve as non-invasive indicators of sub-clinical cardiac stress, which could be relevant for anaesthetic risk assessment and perinatal management.

MedicinaVol. 61(5)
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Harran University (TR)
Good health and well-being
Openalex Percentile: Top 10%
Cardiovascular Issues in Pregnancy
2.78
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.