High-Sensitivity PD-L1 Staining Using Clone 73−10 Antibody and Spatial Transcriptomics for Precise Expression Analysis in Non-Tumorous, Intraepithelial Neoplasia, and Squamous Cell Carcinoma of Head and Neck
Clone 73 - 10 is a relatively suitable candidate for identifying patients with PD-L1 expression eligible for ICI therapy. It demonstrates high sensitivity in detecting PD-L1 (CD274) in HNSCC, offering immunological and prognostic insights.
Authors
- Naho Atsumi (ORCID: https://orcid.org/0000-0003-2939-8609)
- Takeo Nakaya (ORCID: https://orcid.org/0000-0002-2672-3528)
- Yuri Noda (ORCID: https://orcid.org/0000-0001-8041-0074)
- Hiroshi Iwai (ORCID: https://orcid.org/0000-0003-2646-8173)
- Koji Tsuta
Institutions
- Kansai Medical University (JP)
Publication Details
- Journal
- Head and Neck Pathology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1007/s12105-025-01798-8
- Citations
- 3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 3.14