Systems Genetics Reveals the Gene Regulatory Mechanisms of Arrb2 in the Development of Autism Spectrum Disorders
This study highlights the role of <i>Arrb2</i> in ASD pathogenesis and identifies <i>Myh9</i>, <i>Dnmt1</i>, and <i>Brd4</i> as key downstream regulators. These findings provide new insights into the molecular mechanisms of ASD and pave the way for novel therapeutic targets.
Authors
- Akhilesh Kumar Bajpai (ORCID: https://orcid.org/0000-0001-9023-1790)
- Yating Dong (ORCID: https://orcid.org/0000-0002-0268-2995)
- Yamei Liu (ORCID: https://orcid.org/0000-0002-0770-8381)
- Shini Feng (ORCID: https://orcid.org/0000-0001-9225-067X)
- Lu Lu (ORCID: https://orcid.org/0000-0002-4815-0724)
- Feng Li (ORCID: https://orcid.org/0000-0002-2616-5343)
- Lele Yu
- Junyu Xia
- Fuxue Chen (ORCID: https://orcid.org/0000-0001-5258-6806)
Institutions
- Shanghai University (CN)
- University of Tennessee Health Science Center (US)
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Genes
- Published
- 2025-05-20
- DOI
- https://doi.org/10.3390/genes16050605
- Citations
- 2
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Natural Science Foundation of China