Kindlin-2 silencing promoted apoptosis and cell cycle arrest through the fas/FasL pathway in hepatocellular carcinoma
This study revealed that Kindlin-2 inhibited apoptosis in HCC by negatively regulating the Fas/FasL signaling pathway. Kindlin-2 reduced apoptosis in HCC cells by suppressing the activation of the Fas/FasL pathway, thereby promoting tumor progression.
Authors
- Shugang Wang (ORCID: https://orcid.org/0000-0001-5414-3726)
- Yan Wang (ORCID: https://orcid.org/0000-0003-2563-255X)
- Weiwei Yu (ORCID: https://orcid.org/0000-0002-8081-6418)
Institutions
- Yantaishan Hospital (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-05-04
- DOI
- https://doi.org/10.1080/08923973.2025.2506696
- Citations
- 2
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 3.24