The Reliability and Accuracy of Magnetic Resonance Imaging for the Diagnosis of Malignant Breast Lesions

Objective: Examining the reliability of magnetic resonance spectroscopy in diagnosing malignant breast lesions, with histology serving as the gold standard, is the objective of this study. Methods: In this cross-sectional research 110 females were included. Before collecting data, patients signed a consent form acknowledging the risks. Dynamically enhanced magnetic resonance (MRS) images were studied for their kinematics and morphology. MRS's choline peak (Cho) was used to detect cancer. Single-voxel technique was used to evaluate MRS' diagnostic accuracy in cancer. MRS and biopsies were compared. Results: The patients mean age was 48.13±12.54 years and had mean BMI 26.25±9.61 kg/m2. Histological analysis revealed malignant lesions in 82 cases (74.5%), whereas magnetic resonance imaging (MRI) confirmed the presence of malignant lesions in 90 patients (81.8%). When using MRS to diagnose malignant tumors, the most common morphologies observed were ductal enhancement and peripheral enhancement. In terms of specificity, accuracy, sensitivity, NPV, and PPV, MRS demonstrated a performance of 88%, 92%, 72%, and 94%, respectively. Conclusion: The superior specificity, sensitivity, and accuracy of MRS make it an indispensable tool for identifying breast masses. When it comes to diagnosing breast cancer, MRS is a specialized, sensitive, and efficient method.

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Publication Details

Journal
Indus journal of bioscience research.
Published
2025-05-08
DOI
https://doi.org/10.70749/ijbr.v3i5.1409
Primary Topic
Infrared Thermography in Medicine
Type
article
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The Reliability and Accuracy of Magnetic Resonance Imaging for the Diagnosis of Malignant Breast Lesions

Syed Naseer Ahmed
Indus journal of bioscience research.
Infrared Thermography in Medicine
article

The Reliability and Accuracy of Magnetic Resonance Imaging for the Diagnosis of Malignant Breast Lesions

Syed Naseer Ahmed
article en

Abstract

Objective: Examining the reliability of magnetic resonance spectroscopy in diagnosing malignant breast lesions, with histology serving as the gold standard, is the objective of this study. Methods: In this cross-sectional research 110 females were included. Before collecting data, patients signed a consent form acknowledging the risks. Dynamically enhanced magnetic resonance (MRS) images were studied for their kinematics and morphology. MRS's choline peak (Cho) was used to detect cancer. Single-voxel technique was used to evaluate MRS' diagnostic accuracy in cancer. MRS and biopsies were compared. Results: The patients mean age was 48.13±12.54 years and had mean BMI 26.25±9.61 kg/m2. Histological analysis revealed malignant lesions in 82 cases (74.5%), whereas magnetic resonance imaging (MRI) confirmed the presence of malignant lesions in 90 patients (81.8%). When using MRS to diagnose malignant tumors, the most common morphologies observed were ductal enhancement and peripheral enhancement. In terms of specificity, accuracy, sensitivity, NPV, and PPV, MRS demonstrated a performance of 88%, 92%, 72%, and 94%, respectively. Conclusion: The superior specificity, sensitivity, and accuracy of MRS make it an indispensable tool for identifying breast masses. When it comes to diagnosing breast cancer, MRS is a specialized, sensitive, and efficient method.

Indus journal of bioscience research.Vol. 3(5)
Shaikh Zayed Hospital (PK), Shaikh Khalifa Medical City (AE)
Openalex Percentile: Top 83%
Infrared Thermography in Medicine
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The Reliability and Accuracy of Magnetic Resonance Imaging for the Diagnosis of Malignant Breast Lesions — Syed Naseer Ahmed · Indus journal of bioscience research. (2025) | TGRS Research Map | TGRS