Directed Cascade C–H Functionalization/2-Fold Annulation with Vinylcyclopropanes: Access to Tetrahydrobenzo[<i>g</i>]isochromen-10-ones
Rh-catalyzed enaminone directed cascade C-H functionalization/2-fold annulation with vinylcyclopropanes has been accomplished to afford functionalized tetrahydrobenzo[<i>g</i>]isochromen-10-ones. The sequential C-H/C-C functionalization, C-C/C-O bond formation, redox-neutral conditions, functional group tolerance, and late-stage modification of the natural products are important practical features.
Authors
- Tharmalingam Punniyamurthy (ORCID: https://orcid.org/0000-0003-4696-8896)
- Tripti Paul (ORCID: https://orcid.org/0000-0001-9240-7745)
- Shubhajit Basak (ORCID: https://orcid.org/0000-0002-0315-4158)
- Maniya V. Nanjegowda (ORCID: https://orcid.org/0009-0006-9015-9745)
- Madhab Barman
Institutions
- Indian Institute of Technology Guwahati (IN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1021/acs.orglett.5c01312
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- University Grants Commission
- Ministry of Education, India
- Science and Engineering Research Board