Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is false positive: a case report

Our case illustrates a sporadically recognized false-positive prostate-specific membrane antigen positron emission tomography-computed tomography finding associated with a bounce phenomenon following low-dose-rate brachytherapy for prostate cancer. A single prostate-specific antigen test effectively ruled out the suspicion of local recurrence. While prostate-specific membrane antigen positron emission tomography-computed tomography is undoubtedly a valuable tool for detecting metastasis postoperatively, careful interpretation of local findings is essential owing to the potential for false positives. This consideration is vital when evaluating a patient with a rising prostate-specific antigen level after brachytherapy, to avoid premature initiation of salvage therapy.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-05-20
DOI
https://doi.org/10.1186/s13256-025-05268-1
Citations
1
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is false positive: a case report

Daniel Engeler, Hans‐Peter Schmid, Christoph Schwab, Tamas Rozsos
1 citations
Journal of Medical Case Reports
Prostate Cancer Diagnosis and Treatment
1.52
article

Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is false positive: a case report

Daniel Engeler, Hans‐Peter Schmid, Christoph Schwab, Tamas Rozsos
article en
1 citations

Abstract

Our case illustrates a sporadically recognized false-positive prostate-specific membrane antigen positron emission tomography-computed tomography finding associated with a bounce phenomenon following low-dose-rate brachytherapy for prostate cancer. A single prostate-specific antigen test effectively ruled out the suspicion of local recurrence. While prostate-specific membrane antigen positron emission tomography-computed tomography is undoubtedly a valuable tool for detecting metastasis postoperatively, careful interpretation of local findings is essential owing to the potential for false positives. This consideration is vital when evaluating a patient with a rising prostate-specific antigen level after brachytherapy, to avoid premature initiation of salvage therapy.

Journal of Medical Case ReportsVol. 19(1)
Kantonsspital St. Gallen (CH)
Openalex Percentile: Top 18%
Prostate Cancer Diagnosis and Treatment
1.52
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Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography–computed tomography is false positive: a case report — Daniel Engeler, Hans‐Peter Schmid, et al. · Journal of Medical Case Reports (2025) | TGRS Research Map | TGRS