Combining sodium-glucose co-transporter-2 inhibitor with mesenchymal stem cells and brown adipose tissue (BAT) and white adipose tissue (WAT) transplantation to mitigate the progression of diabetic kidney disease: a pre-clinical approach
BM-MSC therapy demonstrates considerable promise as a combined treatment for mitigating DKD progression, with similar findings observed for BAT and WAT transplantation.
Authors
- Marcella Liciani Franco (ORCID: https://orcid.org/0000-0002-9990-6018)
- Maria Theresa A Balby-Rocha (ORCID: https://orcid.org/0000-0001-9339-7470)
- Bianca Vitória dos Santos Barbosa
- Marcella Klein
- J.E. Arjona
- Andrei Furlan da Silva
- Stephany Beyerstedt (ORCID: https://orcid.org/0000-0002-3307-1644)
- Melise Oliveira Mariano (ORCID: https://orcid.org/0009-0006-1632-5442)
- Érika Bevilaqua Rangel (ORCID: https://orcid.org/0000-0003-0982-2484)
- Gleice Regina Josefi-Rocha (ORCID: https://orcid.org/0000-0002-3319-760X)
- Tuany Marques Reiter Alves
- A D S Carlos
Institutions
- Hospital Israelita Albert Einstein (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s13287-025-04358-7
- Citations
- 1
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- European Foundation for the Study of Diabetes
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior