Deescalation From Ticagrelor to Clopidogrel for Myocardial Infarction With Chronic Kidney Disease
In this secondary analysis of a randomized clinical trial, deescalation from ticagrelor to clopidogrel at 1 month after PCI for AMI was associated with significant reduction in bleeding without increased risk of ischemic events among study-eligible patients with CKD. Further adequately powered studies are needed to validate these findings.
Authors
- Myunhee Lee (ORCID: https://orcid.org/0000-0002-0658-4081)
- Jang Hoon Lee (ORCID: https://orcid.org/0000-0002-7101-0236)
- Jae‐Sik Jang (ORCID: https://orcid.org/0000-0001-7865-124X)
- Eun Ho Choo (ORCID: https://orcid.org/0000-0003-3166-3176)
- Kiyuk Chang (ORCID: https://orcid.org/0000-0003-3456-8705)
- Young Kyoung (ORCID: https://orcid.org/0000-0001-9996-6224)
- Jaeho Byeon (ORCID: https://orcid.org/0000-0002-6981-6732)
- Ik Jun Choi (ORCID: https://orcid.org/0000-0001-9996-2346)
- Kwang Soo
- Kwan Yong Lee (ORCID: https://orcid.org/0000-0002-0480-1046)
- Yun Seok Choi (ORCID: https://orcid.org/0000-0002-1659-1728)
- Byung‐Hee Hwang (ORCID: https://orcid.org/0000-0001-7770-0791)
- Joon Ho Hyeong
- Chul Soo Park (ORCID: https://orcid.org/0000-0002-0180-9149)
- Chang Hyeon Cho
- Chan Joon Kim (ORCID: https://orcid.org/0000-0003-2929-8325)
- Mahn‐Won Park (ORCID: https://orcid.org/0000-0001-5293-8461)
- Sungmin Lim (ORCID: https://orcid.org/0000-0001-7071-5675)
- Seung Ho Huh
- Byung Ryeol Cho
- Ki‐Chul Sung (ORCID: https://orcid.org/0000-0001-5630-2145)
- Ju Hyun Oh (ORCID: https://orcid.org/0000-0003-0756-3810)
- Jin Man Cho (ORCID: https://orcid.org/0000-0003-3696-3557)
- Dong‐Bin Kim (ORCID: https://orcid.org/0000-0002-0219-190X)
- Sung‐Ho Her (ORCID: https://orcid.org/0000-0002-1548-4154)
- Won Bae Kim (ORCID: https://orcid.org/0000-0003-4544-1750)
- Sang Hyun Kim (ORCID: https://orcid.org/0000-0002-5668-6502)
- Yong Hoon Cho (ORCID: https://orcid.org/0000-0003-0170-9997)
- Sang‐Wook Kim (ORCID: https://orcid.org/0000-0002-7208-8596)
- Sang‐Ho Park (ORCID: https://orcid.org/0000-0001-7912-0336)
- Jong Sun Park (ORCID: https://orcid.org/0000-0003-3707-3636)
- Myung Ho Jeong (ORCID: https://orcid.org/0000-0003-2424-810X)
- Kyung Min Park
- Seoung Hwan Lee
- Joo Yeol Baek
- Chul‐Soo Park (ORCID: https://orcid.org/0000-0003-0530-7960)
- Sang Hyeon Kim
- Byung Joo Shim
- Jin Shin Ko
- Sang Shik Jung
- Kyung Tae Chung
- Woo Seung Shin
- Ki Sik Kim
- Myung Ho Yoon
Institutions
- San Diego State University (US)
- The Catholic University of Korea St. Vincent's Hospital (KR)
- The Catholic University of Korea Incheon St. Mary's Hospital (KR)
- The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR)
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- The Catholic University of Korea Daejeon St. Mary's Hospital (KR)
- Armed Forces Capital Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.11297
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00