Variables associated with cognitive alterations in a cohort of COVID-19 survivors at a tertiary hospital in Mexico
Our study suggests that COVID-19 survivors who had moderate-to-severe infection experience subjective complaints and cognitive impairments in executive function, attention, and memory, regardless of whether invasive mechanical ventilation was used during treatment. We found white matter lesions and cerebral atrophy in frontal and parietal regions that were associated with cognitive deficits. Our findings highlight the clinical need for longitudinal programmes capable of evaluating the real impact of SARS-CoV-2 infection on the central nervous system, particularly in the cognitive and emotional domains.
Authors
- Alonso Gutiérrez‐Romero (ORCID: https://orcid.org/0000-0001-6881-4770)
- María Rodríguez-Rodríguez
- Armando Castorena-Maldonado
- D. López-González
- Roger Carrillo‐Mezo (ORCID: https://orcid.org/0000-0001-8719-4589)
- Yaneth Rodríguez‐Agudelo (ORCID: https://orcid.org/0000-0003-0900-684X)
- M. González-Navarro (ORCID: https://orcid.org/0000-0001-7710-9774)
- O. Marrufo (ORCID: https://orcid.org/0000-0001-9953-3947)
- Antonio Araúz (ORCID: https://orcid.org/0000-0002-3340-4138)
- Mireya Chávez-Oliveros
- Susana Lozano-Tovar (ORCID: https://orcid.org/0000-0002-4853-8438)
- Manuel Del Río Quiñones
- F.J. Soto-Moreno
- K. González-Alonso
- Francisco Paz-Rodríguez (ORCID: https://orcid.org/0000-0003-4424-7067)
- A. García-Santos
Institutions
- Instituto Nacional de Enfermedades Respiratorias (MX)
- Instituto Nacional de Neurología y Neurocirugía (MX)
Publication Details
- Journal
- Neurología (English Edition)
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.nrleng.2025.05.002
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00