Fulminant lymphocytic myocarditis with unusual giant cell detection: a case report
The multinucleated giant cell formation might be the accidental result of the fusion of macrophages that had ingested myocardial calcifications or degenerative macromolecules formed by the severe inflammatory process of lymphocytic myocarditis. The massive calcium deposition in both ventricles on CT and the positivity of monocytic markers in giant cells support this hypothesis.
Authors
- Osamu Seguchi (ORCID: https://orcid.org/0000-0003-0820-9629)
- Yasumasa Tsukamoto (ORCID: https://orcid.org/0000-0002-0963-6940)
- Satsuki Fukushima (ORCID: https://orcid.org/0000-0002-9481-8860)
- Takuma Sato (ORCID: https://orcid.org/0000-0002-7006-390X)
- Yoshihiko Ikeda (ORCID: https://orcid.org/0000-0001-6395-5072)
Institutions
- National Cerebral and Cardiovascular Center (JP)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1093/ehjcr/ytaf248
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00