A retrospective analysis of vortioxetine utilization in children and adolescents with major depressive disorder in clinical practice

There exists a certain proportion of children and adolescents suffering from depression who are prescribed vortioxetine in an off-label manner in psychiatric clinics. Vortioxetine demonstrates well tolerability in clinical practice. However, the proportion of self-report symptom alleviation is comparatively unsatisfactory. Furthermore, gender appears influence on self-report symptom relief.

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Publication Details

Journal
BMC Psychiatry
Published
2025-05-20
DOI
https://doi.org/10.1186/s12888-025-06983-1
Citations
1
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
1.39

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article

A retrospective analysis of vortioxetine utilization in children and adolescents with major depressive disorder in clinical practice

Xianmei Luo, Handi Zhang, Mingjun Duan, Keliang Pan et al.
1 citations
BMC Psychiatry
Treatment of Major Depression
1.39
article

A retrospective analysis of vortioxetine utilization in children and adolescents with major depressive disorder in clinical practice

Xianmei Luo, Handi Zhang, Mingjun Duan, Keliang Pan, Shu Yu, Yajun Zhang, Lin Cheng, Fan Luo
article en
1 citations

Abstract

There exists a certain proportion of children and adolescents suffering from depression who are prescribed vortioxetine in an off-label manner in psychiatric clinics. Vortioxetine demonstrates well tolerability in clinical practice. However, the proportion of self-report symptom alleviation is comparatively unsatisfactory. Furthermore, gender appears influence on self-report symptom relief.

BMC PsychiatryVol. 25(1)
University of Electronic Science and Technology of China (CN), Shantou University Mental Health Center (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 20%
Treatment of Major Depression
1.39
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