Impact of cytomegalovirus DNAemia detected by next-generation sequencing on short-term prognosis after lung transplantation
mNGS revealed a higher incidence of early CMV DNAemia post-lung transplantation than previously reported. CMV DNAemia significantly correlates with poor prognosis. Despite limitations in sample size and retrospective design, this study provides novel insights into CMV monitoring and management post-transplantation. Future research should determine optimal timing for preemptive antiviral strategies guided by mNGS.
Authors
- Chenhao Xuan (ORCID: https://orcid.org/0009-0000-9653-8064)
- Zhongping Xu
- Zhiyu Li (ORCID: https://orcid.org/0000-0003-1666-9115)
- Dapeng Wang (ORCID: https://orcid.org/0000-0002-9925-4574)
- Yinan Zhang (ORCID: https://orcid.org/0000-0002-0357-3926)
- Hongyang Xu (ORCID: https://orcid.org/0000-0001-5003-4282)
Institutions
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- Infectious Medicine
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.imj.2025.100185
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nanjing Medical University