A formal vinylogous Schmidt reaction: nitrogen insertion of <i>para</i> -quinone methides
We report a facile introduction of a nitrogen-containing group into p -QM substrates, which delivering the benzoxazolidine motif through a formal vinylogous Schmidt process or the dihydroindazole scaffold via a 1,6-addition/cyclization step.
Authors
- Yin-Xue Zhi
- Chen Zhu (ORCID: https://orcid.org/0000-0002-8997-2281)
- Qingqiang Yao (ORCID: https://orcid.org/0000-0001-7891-8661)
- Hongmin Zhu (ORCID: https://orcid.org/0000-0001-9747-4533)
- Xin Zhao
- Tiandi Ding (ORCID: https://orcid.org/0000-0001-7892-2943)
- Magnus Rueping (ORCID: https://orcid.org/0000-0003-4580-5227)
- Yanhao Dong (ORCID: https://orcid.org/0000-0003-1224-1015)
- Chen Kong (ORCID: https://orcid.org/0000-0002-9908-6726)
- Bo Wang (ORCID: https://orcid.org/0000-0002-6581-7316)
- Y. Yang (ORCID: https://orcid.org/0000-0002-8917-2620)
- Yan Li (ORCID: https://orcid.org/0000-0002-2708-123X)
- Kun Zhao (ORCID: https://orcid.org/0000-0002-5623-4258)
- Guoyue Wei
Institutions
- Shandong University (CN)
- Shandong First Medical University (CN)
- Eastern Institute of Technology, Ningbo
- King Abdullah University of Science and Technology (SA)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00476d
- Citations
- 1
- Primary Topic
- Synthesis of Indole Derivatives
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province