Development of a clinical prediction model for sensitivity to combination therapy of Bcl-2 inhibitors and hypomethylating agents in elderly/unfit patients with acute myeloid leukemia
A prediction model was developed and validated to serve as a decision-making tool for physicians treating elderly/unfit patients with AML prior to initiating therapy with Bcl-2 inhibitors combined with HMAs.
Authors
- Yufeng Du (ORCID: https://orcid.org/0000-0003-3159-9629)
- Fang Xie (ORCID: https://orcid.org/0000-0002-6121-0875)
- Yonghong Chen (ORCID: https://orcid.org/0000-0002-6509-4357)
- Jinsong Yan (ORCID: https://orcid.org/0000-0003-4109-2602)
- Chunhong Li (ORCID: https://orcid.org/0000-0002-7133-0301)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1007/s12672-025-02612-1
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77