Sex differences in pre- and post-surgical left ventricular remodelling and outcomes in primary mitral regurgitation
In primary MR there were no sex differences in the degree of pre-surgical LV dilatation or post-surgical LV reverse remodelling. There were no sex differences in adverse clinical events. These findings highlight that males and females benefit similarly from mitral valve surgery and females should be referred for mitral valve surgery when appropriate.(Clinical Trials: NCT04038879, NCT03012178, and NCT04051411).
Authors
- Michael Langer
- Ibrahim Sultan (ORCID: https://orcid.org/0000-0002-1737-4012)
- Andrew D. Choi (ORCID: https://orcid.org/0000-0003-1500-0428)
- Marco Guglielmo (ORCID: https://orcid.org/0000-0003-1718-9949)
- Robert W Biederman (ORCID: https://orcid.org/0000-0003-3931-3461)
- Seth Uretsky (ORCID: https://orcid.org/0000-0002-6361-1509)
- João L. Cavalcante (ORCID: https://orcid.org/0000-0002-3632-2074)
- Dipan J. Shah (ORCID: https://orcid.org/0000-0002-6179-2393)
- Ron Jacob (ORCID: https://orcid.org/0000-0002-1626-1120)
- Matthew Tong (ORCID: https://orcid.org/0000-0003-2482-1324)
- Gianluca Pontone (ORCID: https://orcid.org/0000-0002-1339-6679)
- Yuchi Han (ORCID: https://orcid.org/0000-0001-7582-1848)
- Sakul Sakul
- Linda D. Gillam (ORCID: https://orcid.org/0000-0002-1716-7574)
- Steven Wolff
- Edward T. Martin
Institutions
- Houston Methodist (US)
- Mount Sinai Hospital (US)
- Medical University of South Carolina (US)
- George Washington University (US)
- Morristown Medical Center (US)
- The Ohio State University Wexner Medical Center (US)
- St. Luke's Hospital (US)
- Centro Cardiologico Monzino (IT)
- Saint Francis Hospital (US)
- Oklahoma Heart Institute (US)
- Mount Sinai Hospital (US)
- Roper Hospital (US)
- Eastside Comprehensive Medical Center (US)
- Minneapolis Heart Institute Foundation (US)
- University of Pittsburgh Medical Center (US)
- WellSpan York Hospital (US)
- The Ohio State University (US)
- Atlantic Health System (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Imaging
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1093/ehjci/jeaf151
- Citations
- 3
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.16