Investigating the neural correlates of subjective sleep changes following subthalamic nucleus deep brain stimulation for Parkinson's disease

Our findings suggest that STN-DBS may modulate sleep via broader structural connections and beyond motor symptom improvements. The lateralised effects and involvement of widespread tracts underscore the complexity of DBS-related sleep modulation. Future studies should incorporate longitudinal designs and objective measures to disentangle motor-independent mechanisms and optimise therapeutic strategies.