Nationwide analysis on the role of neoadjuvant radiotherapy and watch and wait in rectal cancer
This population-based nationwide study showed that over half of all non-metastasized rectal cancer patients underwent neoadjuvant treatment. The overall successful one-year organ preservation rate was 17 %, of which 2 % with the addition of local excision. The watch and wait approach has been widely adopted within the national healthcare system as an alternative to surgery for patients with a clinical complete response.
Authors
- Cornelis Verhoef (ORCID: https://orcid.org/0000-0001-9980-8613)
- Stefan Buettner (ORCID: https://orcid.org/0000-0002-0942-127X)
- Henderik L. van Westreenen (ORCID: https://orcid.org/0000-0002-1910-2723)
- Marlou F. M. Sterk
- Pim B. Olthof (ORCID: https://orcid.org/0000-0002-1691-1808)
- Denise E. Hilling (ORCID: https://orcid.org/0000-0002-5875-6164)
- Johanne G. Bloemen
- A. R. Wijsmuller
- Vincent Meyer (ORCID: https://orcid.org/0000-0003-1348-7973)
- Klaas Havenga
- Geerard L. Beets (ORCID: https://orcid.org/0000-0002-1671-9912)
- Robert R.J. Coebergh van den Braak (ORCID: https://orcid.org/0000-0001-9310-6629)
- David M Mens (ORCID: https://orcid.org/0009-0000-2247-5048)
Institutions
- University Medical Center Groningen (NL)
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Amphia Ziekenhuis (NL)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Isala (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1016/j.ejso.2025.110179
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05