DNA methylation regulates growth traits by influencing metabolic pathways in Pacific white shrimp (Litopenaeus vannamei)
DNA methylation plays a role in the regulation of growth traits in L. vannamei. The level of DNA methylation was found to be negatively correlated with growth traits. Through comprehensive analysis, it was discovered that DNA methylation predominantly affects growth performance by up-regulating the expression of genes involved in metabolic pathways, such as glucose metabolism and amino acid metabolism in L. vannamei. This suggests a higher metabolism activity in SG individuals derived DNA methylation to cope with some unknown internal stress or environmental stress rather than being allocated for growth.
Authors
- Bo Ma (ORCID: https://orcid.org/0000-0002-5867-1718)
- Yunyi Huang
- Li Huo (ORCID: https://orcid.org/0000-0003-1216-083X)
- Pengying Li
- Peng Luo (ORCID: https://orcid.org/0000-0002-8215-2045)
- Yehui Tan (ORCID: https://orcid.org/0000-0002-6378-2156)
- Xiao Jiang (ORCID: https://orcid.org/0000-0001-7030-848X)
- Yanhong Wang (ORCID: https://orcid.org/0000-0002-8378-4925)
- Ting Chen (ORCID: https://orcid.org/0000-0001-8414-6346)
- Liyan Liu (ORCID: https://orcid.org/0000-0003-1941-1689)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-0501-3439)
- Jiayue Yin
- Chaoqun Hu (ORCID: https://orcid.org/0000-0002-1918-4888)
- Chunhua Ren (ORCID: https://orcid.org/0000-0002-7458-1923)
Institutions
- South China Sea Institute Of Oceanology (CN)
- Beike Biotechnology (China) (CN)
- Zhanjiang Experimental Station (CN)
- University of Chinese Academy of Sciences (CN)
- Shanghai Ocean University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1186/s12864-025-11688-6
- Citations
- 5
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Chinese Academy of Sciences
- National Key Research and Development Program of China
- Science and Technology Planning Project of Guangdong Province