Significance of androgen receptor and its potential for anti-androgen/androgen receptor-antagonist therapy in ovarian cancers
AR is expressed in a high percentage of OCs, even more frequently than ER and PR in certain high-grade histological types. Overall, our findings are similar to the results of recent studies of AR expression in endometrial cancers. These findings support an important possible role for AR in OCs as a potential marker to serve as a therapeutic target in these malignancies.
Authors
- Neda A. Moatamed (ORCID: https://orcid.org/0000-0002-9986-8058)
- Sanaz Memarzadeh
- Nora Ostrzega
- Saba Vahdatshariatpanahi (ORCID: https://orcid.org/0009-0005-4706-1622)
- Teresa Kim (ORCID: https://orcid.org/0000-0003-1404-0479)
- Yuna Kang (ORCID: https://orcid.org/0009-0003-3505-2580)
Institutions
- University of Southern California (US)
- University of California, Los Angeles (US)
- Broad Center (US)
- VA Greater Los Angeles Healthcare System (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1371/journal.pone.0322744
- Citations
- 1
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- U.S. Department of Veterans Affairs