Burns results in profound muscle protein wasting in Sprague Dawley rats that is not resolved using the lipolysis inhibitor, acipimox
In a rodent model of burns, the loss of muscle mass primarily occurs due to the acceleration of muscle proteolysis, independent of any change in muscle lipid content.
Authors
- Doaa R. Abdelrahman (ORCID: https://orcid.org/0000-0001-9847-5714)
- Emre Vardarli
- Andrew J. Murton (ORCID: https://orcid.org/0000-0002-9474-9113)
- Victoria G. Rontoyanni (ORCID: https://orcid.org/0000-0002-6608-496X)
- Nisha Bhattarai (ORCID: https://orcid.org/0000-0002-5595-1474)
- Amina El Ayadi (ORCID: https://orcid.org/0000-0002-3657-0633)
- Anesh Prasai (ORCID: https://orcid.org/0000-0002-2598-9105)
Institutions
- Shriners Hospitals for Children - Galveston (US)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1371/journal.pone.0323640
- Citations
- 1
- Primary Topic
- Burn Injury Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Shriners Hospitals for Children