Spatial Transcriptomics Advances the Use of Canine Patients in Cancer Research: Analysis of Osteosarcoma-Bearing Pet Dogs Enrolled in a Clinical Trial
Gene and pathway enrichment found to be associated with DFI in this study overlap with that described in human patients with osteosarcoma, underscoring the value of the canine model in metastatic osteosarcoma research.
Authors
- Amy K. LeBlanc (ORCID: https://orcid.org/0000-0001-7656-9859)
- Jessica A. Beck (ORCID: https://orcid.org/0000-0002-0145-7606)
- S. Church (ORCID: https://orcid.org/0000-0002-7194-4282)
- Anjali Garg (ORCID: https://orcid.org/0000-0001-9981-3607)
- Christina Mazcko
Institutions
- National Institutes of Health (US)
- Nanostring Technologies (United States) (US)
- National Cancer Institute (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-05-20
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-0687
- Citations
- 2
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Cancer Institute