Mammary manifestation of Systemic Lupus Erythematosus in patient with associated scleroderma: a case report

Systemic Lupus Erythematosus is an autoimmune disease of ill-defined etiology that is presented in different forms throughout its natural history. The clinical manifestations end up affecting several tissues and organs of the body. A rare manifestation of this disease is lupus panniculitis, which, when affecting the breast tissue, is called lupus mastitis. Likewise, scleroderma can occur, an autoimmune disease that affects the connective tissue and can manifest systemically (systemic sclerosis) or locally and affect tissues in varying histologic grades. The prevalence is higher in women for both Systemic Lupus Erythematosus and scleroderma, justifying the importance of correlating the manifestation of these diseases with their impacts on women's health. The presented case is of a 58-year-old woman who presented a nodule in the left breast, with progression to hardening of the lesion and the breast. The evolution of the case was carried out with clinical follow-up of the condition together with the specialties of rheumatology and mastology. In the present study, we aim to report an atypical case of the manifestation of Systemic Lupus Erythematosus and scleroderma in the breast and to review the literature.