Utilization of Computed Tomography Colonography (CTC) at a District General Hospital: A Retrospective Analysis

Colorectal cancer (CRC) is one of the most common cancers worldwide, necessitating efficient diagnostic pathways. While colonoscopy remains the gold standard, computed tomography colonography (CTC) offers a non-invasive alternative, particularly for elderly and comorbid patients. This retrospective study, conducted at a UK district general hospital (DGH), evaluated patterns of CTC utilization among patients referred for colonic investigations over a 12-month period. Despite CTC's high diagnostic accuracy (93% sensitivity for polyps > 10 mm) and its suitability for high-risk populations, it was used as a first-line investigation in only 3.5% of cases, markedly lower than the 12%-15% reported in tertiary centers. Contributing factors included limited radiologist training, restricted CT scanner capacity, and a prevailing institutional preference for colonoscopy. Addressing these DGH-specific barriers, such as resource constraints and workforce limitations, is critical to enhancing CTC's role within the two-week-wait (2WW) pathway. This study underscores the need for multicenter research to validate these findings and guide policy development, ensuring equitable access to non-invasive diagnostics for frail, comorbid, or preference-driven populations.

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Publication Details

Journal
Cureus
Published
2025-05-20
DOI
https://doi.org/10.7759/cureus.84490
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
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0.00
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article

Utilization of Computed Tomography Colonography (CTC) at a District General Hospital: A Retrospective Analysis

Nafees Qureshi, Harry Large, Kehkashan Anwar, Ehtisham Zeb et al.
1 links
Cureus
Colorectal Cancer Screening and Detection
article

Utilization of Computed Tomography Colonography (CTC) at a District General Hospital: A Retrospective Analysis

Nafees Qureshi, Harry Large, Kehkashan Anwar, Ehtisham Zeb, Ali Javaid
article en

Abstract

Colorectal cancer (CRC) is one of the most common cancers worldwide, necessitating efficient diagnostic pathways. While colonoscopy remains the gold standard, computed tomography colonography (CTC) offers a non-invasive alternative, particularly for elderly and comorbid patients. This retrospective study, conducted at a UK district general hospital (DGH), evaluated patterns of CTC utilization among patients referred for colonic investigations over a 12-month period. Despite CTC's high diagnostic accuracy (93% sensitivity for polyps > 10 mm) and its suitability for high-risk populations, it was used as a first-line investigation in only 3.5% of cases, markedly lower than the 12%-15% reported in tertiary centers. Contributing factors included limited radiologist training, restricted CT scanner capacity, and a prevailing institutional preference for colonoscopy. Addressing these DGH-specific barriers, such as resource constraints and workforce limitations, is critical to enhancing CTC's role within the two-week-wait (2WW) pathway. This study underscores the need for multicenter research to validate these findings and guide policy development, ensuring equitable access to non-invasive diagnostics for frail, comorbid, or preference-driven populations.

CureusVol. 17(5)
Tameside and Glossop Integrated Care NHS Foundation Trust (GB)
Openalex Percentile: Top 83%
Colorectal Cancer Screening and Detection
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